Vitamin/mineral
|
Brain function
|
Sources
|
Folate, folic acid (Vitamin B9) |
- Can heighten serotonin function by slowing destruction of tryptophan
- Cofactor for enzymes that convert tryptophan into serotonin and convert tyrosine into norepinephrine/noradrenalin
- Helps form compounds involved in brain energy metabolism
- Involved in synthesis of monoamine neurotransmitters
|
Dark green leafy vegetables |
Cobalamin (Vitamin B12) |
- Helps synthesize monoamine neurotransmitters
- Helps maintain myelin sheaths on nerves for normal nerve conductance.
- Functions in folate metabolism
|
Fish, shellfish, poultry, other meat (especially liver), and milk products |
Thiamine (Vitamin B1) |
- Involved in synthesis of acetylcholine, GABA, and glutamate
- Can mimic action of acetylcholine in the brain
|
Yeast, yeast extract, and pork |
Pyridoxine (Vitamin B6) |
- Plays a basic role in synthesis of many neurotransmitters
- Deficiency tends to selectively reduce brain production of serotonin and GABA
|
Meats, whole-grain products, vegetables, nuts, and bananas |
Vitamin E |
- Protects cell membranes from damage by free radicals
- May play a role in reducing brain amyloid beta peptide accumulation
|
Seed and nut oils |
Choline |
- Plays essential roles in structural integrity of cell membranes, cell signalling, and nerve impulse transmission
- Major source of methyl groups for methylation reactions
|
Beef liver, soy and sunflower lecithin, cauliflower, broccoli |
Calcium |
- Important intracellular messenger and cofactor for enzymes
- Important for release of neurotransmitters and several forms of chemical signalling between cells.
|
Dairy products, seaweed, nuts, seeds, and beans |
Chromium |
- Primarily known for its function in glucose and lipid metabolism, which may account for its role in mood
|
No reliable natural food source |
Iron |
- Essential cofactor for production of ATP energy in the brain.
- Ensures there is sufficient oxygen in the brain for oxidative metabolism.
- Helps produce serotonin, norepinephrine, epinephrine, and dopamine
- Increases binding of dopamine and serotonin to proteins in frontal cortex
|
Red meat, lentils, beans, poultry, fish, leaf vegetables, watercress, tofu, chickpeas, black-eyed peas |
Magnesium |
- Helps in the metabolism of carbohydrates and fats to produce ATP
- Helps in the synthesis of nucleic acids (DNA and RNA) and proteins.
- Important for the active transport of ions (such as potassium and calcium) across cell membranes and for cell signalling.
- Essential for over 300 biochemical reactions in the body
|
Spices, nuts, cereals, coffee, cocoa, tea, and vegetables |
Zinc |
- The most abundant intracellular trace element, with roles extending into protein synthesis, as well as structure and regulation of gene expression
- Cofactor for over 200 different enzymes; present in over 300 metalloenzymes involved in virtually all aspects of metabolism
- In the brain, serves in neurons and glial cells. Certain zinc-enriched regions (e.g., hippocampus) are especially responsive to dietary zinc deprivation, which causes brain dysfunctions, such as learning impairment and olfactory dysfunction
|
Oysters, lobster, and red meats, especially beef, lamb and liver |
Selenium |
- Essential trace mineral which is part of antioxidant enzymes that protect cells from effects of free radicals.
|
Nuts, cereals, meat, mushrooms, fish, and eggs |